ABCD1 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 60153-1-Ig |CloneNo.: 1H8E5

Featured Product KD/KO validated

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Freight/Packing

Con: 150 μg/150 μl

Choose size:

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Species specificity:
human

Positive WB detected in:
HeLa cells

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:2000
IF : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Caprylic acid/ammonium sulfate precipitation

Isotype:
IgG1

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
ATP-binding cassette, sub-family D (ALD), member 1

Calculated molecular weight:
745aa,83 kDa

Observed molecular weight:
75 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ABCD1

Synonyms
ABC42, ABCD1, Adrenoleukodystrophy protein, ALD, ALDP, AMN
Background

ABCD1 (also known as ALDP) is a member of the ATP-binding cassette (ABC) transporter superfamily which functions as transporter for a wide variety of substrates. It localizes to the peroxisomal membrane. The exact function is not clear so far. Various mutations of ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), an inherited neurodegenerative disease affecting the nervous system white matter and adrenal cortex.


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