ADAM19 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 22216-1-AP

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Freight/Packing

Con: 117 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
NIH/3T3 cells

Positive IP detected in:
NIH/3T3 cells

Positive IHC detected in:
human placenta tissue, human placenta tissue, human skeletal muscle tissue

Recommended dilution:
WB : 1:200-1:1000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
ADAM metallopeptidase domain 19 (meltrin beta)

Calculated molecular weight:
955aa,105 kDa

Observed molecular weight:
70 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ADAM19

Synonyms
ADAM 19, ADAM19, FKSG34, MADDAM, Meltrin beta, MLTNB
Background

Meltrinβ(ADAM19) is a metalloprotease-disintegrin expressed in the peripheral nervous system and other organs during embryogenesis. Its specific patterns of expression during embryogenesis suggest that it is involved in the development of the peripheral nervous system, skeletal muscle, bone and heart tissue(PMID:12482604). It participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell.


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