AHCYL1 Antibody 8 Publications

Rabbit Polyclonal| Catalog number: 10658-3-AP

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Freight/Packing

Con: 40 μg/150 μl

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Species specificity:
human, mouse, rat, chicken, Landrace, pig

Positive WB detected in:
Jurkat cells, HeLa cells, mouse thymus tissue

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human liver cancer tissue

Positive IF detected in:
Hela cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:100-1:400
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
S-adenosylhomocysteine hydrolase-like 1

Calculated molecular weight:
65 kDa

Observed molecular weight:
60 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
AHCYL1

Synonyms
AdoHcyase 2, AHCYL1, DCAL, IRBIT, PRO0233, XPVKONA
Background

S-adenosylhomocysteine hydrolase-like protein 1 (AHCYL1), also known as IP3 receptor-binding protein released with IP3 (IRBIT), regulates IP3-induced Ca2+ release into the cytoplasm of cells(PMID:23145124). This protein is also named as DCAL, XPVKONA and belongs to the adenosylhomocysteinase family. AHCYL1 mRNA and protein are most abundant in the glandular epithelium of adenocarcinoma of cancerous, but not normal and AHCYL1 protein is predominantly in the nucleus(PMID:22826361). It has 2 isoforms produced by alternative splicing.


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