AID Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 15642-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
Jurkat cells

Recommended dilution:
WB : 1:500-1:1000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
activation-induced cytidine deaminase

Calculated molecular weight:
198aa,24 kDa

Observed molecular weight:
48-52 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
AICDA

Synonyms
AICDA, AID, ARP2, CDA2, Cytidine aminohydrolase, HIGM2
Background

AID is essential to all three genetic alterations required for antigen-specific immunoglobulin: class switch recombination (CSR), somatic bypermutation (SHM), and gene conversion. Expression of AID is normally restricted to B cells in the GC, where SHM and CSR occur. It is likely these represent AID monomer and homodimer that western blot detected two bands in purified AID from nuclear extracts, one at 52 kDa and the other at 26 kDa. (PMID:16280388)


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