AKT3 Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 21641-1-AP

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Con: 24 μg/150 μl

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Species specificity:
human, mouse, rat, zebrafish

Positive WB detected in:
MCF7 cells, HeLa cells, human brain tissue, K-562 cells, NIH/3T3 cells

Positive IHC detected in:
human kidney tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

Calculated molecular weight:
465aa.54 kDa

Observed molecular weight:
60kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
AKT3

Synonyms
AKT3, DKFZp434N0250, PKB GAMMA, PKBG, PRKBG, Protein kinase Akt 3, Protein kinase B gamma, RAC gamma, RAC PK gamma, STK 2
Background

AKT3, also named as PKBG, is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. AKT3 is a key modulator of several tumors like melanoma, glioma and ovarian cancer. Active AKT3 increases progressively during melanoma tumor progression with highest levels present in advanced-stage metastatic melanomas.


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