ALCAM Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 21972-1-AP

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Freight/Packing

Con: 30 μg/150 μl

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Species specificity:
human

Positive WB detected in:
human liver tissue

Positive IHC detected in:
human breast cancer tissue, human breast cancer tissue, human colon cancer tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
activated leukocyte cell adhesion molecule

Calculated molecular weight:
583aa,65 kDa

Observed molecular weight:
110 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ALCAM

Synonyms
ALCAM, CD166, CD166 antigen, FLJ38514, MEMD
Background

Activated leukocyte cell adhesion molecule (ALCAM, also known as CD166) is a cell adhesion molecule that belongs to the immunoglobulin superfamily. It is involved in cell-cell adhesion through homophilic and heterophilic (to CD6) interactions. ALCAM is widely expressed in a variety of normal tissues. Altered ALCAM expression has been associated with the differentiation state and progression in some neoplasms including melanoma, prostate, colorectal, and breast cancers (PMID: 20461761; 18172759).


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