Tested Applications
| Positive IF/ICC detected in | A431 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
24463-1-AP targets AMTN in WB, IF, IHC, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Cited Reactivity | mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag18439 Product name: Recombinant human AMTN protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-209 aa of BC121817 Sequence: MRSTILLFCLLGSTRSLPQLKPALGLPPTKLAPDQGTLPNQQQSNQVFPSLSLIPLTQMLTLGPDLHLLNPAAGMTPGTQTHPLTLGGLNVQQQLHPHVLPIFVTQLGAQGTILSSEELPQIFTSLIIHSLFPGGILPTSQAGANPDVQDGSLPAGGAGVNPATQGTPAGRLPTPSGTDDDFAVTTPAGIQRSTHAIEEATTESANGIQ Predict reactive species |
| Full Name | amelotin |
| Calculated Molecular Weight | 209 aa, 22 kDa |
| GenBank Accession Number | BC121817 |
| Gene Symbol | AMTN |
| Gene ID (NCBI) | 401138 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q6UX39 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
Amelotin, also named as AMTN, is a novel factor produced by ameloblasts that plays a critical role in the formation of dental enamel.
Publications
What published studies show
The AMTN Polyclonal antibody (Cat# 24463-1-AP) has 3 citations. These publications appear in Oral Diseases, Journal of Molecular Histology, and Developmental Dynamics. The research fields encompass dental enamel formation, odontogenesis, and junctional epithelium biology, with studies conducted in mouse models using IHC, WB, and IF applications.
| Species | Application | Title |
|---|---|---|
Oral Dis Epithelium-Specific Runx2 knockout mice display junctional epithelium and alveolar bone defects. | ||
J Mol Histol Expression and localization of amelotin, laminin γ2 and odontogenesis-associated phosphoprotein (ODAPH) on the basal lamina and junctional epithelium. | ||
Dev Dyn Maturation stage enamel defects in Odontogenesis-associated phosphoprotein (Odaph) deficient mice. |
