BBS3 Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 12676-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 50 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
rat brain tissue, HEK-293 cells, human brain tissue, human testis tissue, mouse brain tissue, rat brain tissue

Positive IP detected in:
rat brain tissue

Positive IHC detected in:
human kidney tissue, human brain tissue, human gliomas tissue, human kidney tissue

Positive IF detected in:
hTERT-RPE1 cells, MDCK cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:500
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
ADP-ribosylation factor-like 6

Calculated molecular weight:
186aa, 21 kDa

Observed molecular weight:
21 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ARL6

Synonyms
ADP ribosylation factor like 6, ARL6, BBS3
Background

ADP-ribosylation factor-like protein 6 (ARL6), belongs to a small GTPase superfamily, is involved in membrane protein trafficking at the base of the ciliary organelle. ARL6 is also named Bardet-Biedl syndrome 3 protein, because defects in ARL6 are a cause of Bardet-Biedl syndrome type 3 (BBS3), which is a genetically heterogeneous disorder characterized by usually severe pigmentary retinopathy, early onset obesity, polydactyly, hypogenitalism, renal malformation and mental retardation. ARL6 can interact with many ARL6 interacting proteins and form BBSome complex with other BBS proteins including BBS1, BBS2, BBS4 and so on.


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