ASNA1 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 15450-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 34 μg/150 μl

Choose size:

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Species specificity:
human, mouse, rat

Positive WB detected in:
human brain tissue, HeLa cells, human heart tissue, mouse brain tissue

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
human lung cancer tissue

Positive IF detected in:
HepG2 cells

Positive FC detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)

Calculated molecular weight:
38.7 kDa

Observed molecular weight:
37-41 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ASNA1

Synonyms
ARSA, ARSA I, ARSA1, ASNA1, ATPase ASNA1, hARSA I, hASNA I, TRC40
Background

ASNA1 (also known as TRC40) is a highly conserved ATPase involved in efflux of arsenite and antimonite. Reduced ASNA1 expression is associated with significant inhibition of cell growth, increased apoptosis and increased sensitivity to cisplatin and arsenite.Thus ASNA1 is proposed to be a target to overcome resistance to cancer chemotherapy. In addition, ASNA1 has been identified as an ER targeting factor for tail-anchored proteins in the posttranslational membrane insertion pathway.


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