ATRX-Specific Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 19788-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Tested Applications

Applications:
ELISA
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Species specificity:
human

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)

Calculated molecular weight:
283 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ATRX

Synonyms
ATP dependent helicase ATRX, ATR2, ATRX, MRXHF1, RAD54, RAD54L, SFM1, SHS, Transcriptional regulator ATRX, X linked helicase II, X linked nuclear protein, XH2, XNP, ZNF HX
Background

ATRX, also named as RAD54L and XH2, belongs to the SNF2/RAD54 helicase family. ATR could be a global transcriptional regulator. ATRX modifies gene expression by affecting chromatin. It may be involved in brain development and facial morphogenesis. Defects in ATRX are the cause of X-linked alpha-thalassemia/mental retardation syndrome (ATR-X) which is an X-linked disorder comprising severe psychomotor retardation, facial dysmorphism, urogenital abnormalities, and alpha-thalassemia. Defects in ATRX are the cause of mental retardation syndromic X-linked with hypotonic facies syndrome type 1 (MRXSHF1) which also called Carpenter-Waziri syndrome (CWS), Juberg-Marsidi syndrome (JMS), Smith-Fineman-Myers syndrome type 1 (SFM1). This antibody is specific to ATRX.


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