ATRX-Specific Polyclonal antibody

ATRX-Specific Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

ELISA

Conjugate

Unconjugated

Cat no : 19788-1-AP

Synonyms

ATP dependent helicase ATRX, ATR2, ATRX, MRXHF1, RAD54, RAD54L, SFM1, SHS, Transcriptional regulator ATRX, X linked helicase II, X linked nuclear protein, XH2, XNP, ZNF HX



Tested Applications

Recommended dilution

ApplicationDilution
Sample-dependent, check data in validation data gallery

Product Information

19788-1-AP targets ATRX-Specific in ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)
Calculated molecular weight 283 kDa
GenBank accession numberNM_000489
Gene symbol ATRX
Gene ID (NCBI) 546
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

ATRX, also named as RAD54L and XH2, belongs to the SNF2/RAD54 helicase family. ATR could be a global transcriptional regulator. ATRX modifies gene expression by affecting chromatin. It may be involved in brain development and facial morphogenesis. Defects in ATRX are the cause of X-linked alpha-thalassemia/mental retardation syndrome (ATR-X) which is an X-linked disorder comprising severe psychomotor retardation, facial dysmorphism, urogenital abnormalities, and alpha-thalassemia. Defects in ATRX are the cause of mental retardation syndromic X-linked with hypotonic facies syndrome type 1 (MRXSHF1) which also called Carpenter-Waziri syndrome (CWS), Juberg-Marsidi syndrome (JMS), Smith-Fineman-Myers syndrome type 1 (SFM1). This antibody is specific to ATRX.