Product Information
10535-1-AP targets B4GALT7 in WB, IF, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag0793 Product name: Recombinant human B4GALT7 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-327 aa of BC007317 Sequence: MFPSRRKAAQLPWEDGRSGLLSGGLPRKCSVFHLFVACLSLGFFSLLWLQLSCSGDVARAVRGQGQETSGPPRACPPEPPPEHWEEDASWGPHRLAVLVPFRERFEELLVFVPHMRRFLSRKKIRHHIYVLNQVDHFRFNRAALINVGFLESSNSTDYIAMHDVDLLPLNEELDYGFPEAGPFHVASPELHPLYHYKTYVGGILLLSKQHYRLCNGMSNRFWGWGREDDEFYRRIKGAGLQLFRPSGITTGYKTFRHLHDPAWRKRDQKRIAAQKQEQFKVDREGGLNTVKYHVASRTALSVGGAPCTVLNIMLDCDKTATPWCTFS Predict reactive species |
| Full Name | xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I) |
| Calculated Molecular Weight | 37 kDa |
| Observed Molecular Weight | 37 kDa |
| GenBank Accession Number | BC007317 |
| Gene Symbol | B4GALT7 |
| Gene ID (NCBI) | 11285 |
| RRID | AB_2274457 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9UBV7 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
B4GALT7 (Beta-1,4-galactosyltransferase 7), also known as galactosyltransferase I, is involved in the formation of proteoglycans which are components of the extracellular matrix in connective tissues (PubMed: 10438455). The reduced activity of B4GALT7 results in delayed wound repair, altered migration, adhesion and contractility of patient fibroblasts (PMID: 16583246, PMID: 18158310). Mutations in B4GALT7 that also result in Spondylodysplastic (PMID: 24755949, PMID: 12417421).
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for B4GALT7 antibody 10535-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
What published studies show
The B4GALT7 Polyclonal antibody (Cat# 10535-1-AP) has 3 total citations published in European Journal of Human Genetics, iScience, and Journal of Medical Virology. The associated research fields include mucopolysaccharidosis (Sanfilippo disease), heparan sulfate biology, and virology (grass carp reovirus and Crimean-Congo Hemorrhagic Fever). Applications cited include WB and IF in human samples.
| Species | Application | Title |
|---|---|---|
Eur J Hum Genet Impairment of glycosaminoglycan synthesis in mucopolysaccharidosis type IIIA cells by using siRNA: a potential therapeutic approach for Sanfilippo disease.
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J Med Virol The Single Amino Acid Change of R516K Enables Efficient Generation of Vesicular Stomatitis Virus-Based Crimean-Congo Hemorrhagic Fever Reporter Virus.
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