BCR-Specific Antibody

BCR-Specific Polyclonal Antibody for IF, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF, ELISA

Conjugate

Unconjugated

Cat no : 19790-1-AP

Synonyms

ALL, BCR, breakpoint cluster region, CML, D22S11, D22S662, PHL



Tested Applications

Recommended dilution

ApplicationDilution
Sample-dependent, check data in validation data gallery

Product Information

19790-1-AP targets BCR-Specific in IF, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name breakpoint cluster region
Calculated molecular weight 143 kDa
Observed molecular weight
GenBank accession number NM_004327
Gene symbol BCR
Gene ID (NCBI) 613
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

BCR, also named as BCR1 and D22S11, is a GTPase-activating protein for RAC1 and CDC42. BCR promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. BCR displays serine/threonine kinase activity. BCR catalyzes the reaction: ATP + a protein = ADP + a phosphoprotein. A chromosomal aberration involving BCR is a cause of chronic myeloid leukemia (CML). The antibody is specific to BCR.