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BCR-Specific Polyclonal antibody

BCR-Specific Polyclonal Antibody for IF,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF, ELISA

Conjugate

Unconjugated

Cat no : 19790-1-AP

Synonyms

ALL, BCR, breakpoint cluster region, CML, D22S11, D22S662, PHL

Validation Data Gallery

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  • Immunofluorescence (IF) / fluorescent staining of HeLa cells using BCR-Specific Polyclonal antibody (19790-1-AP)

    IF Staining of HeLa using 19790-1-AP

    Immunofluorescent analysis of Hela cells, using BCR antibody 19790-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

19790-1-AP targets BCR-Specific in IF, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name breakpoint cluster region
Calculated Molecular Weight 143 kDa
GenBank Accession NumberNM_004327
Gene Symbol BCR
Gene ID (NCBI) 613
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

BCR, also named as BCR1 and D22S11, is a GTPase-activating protein for RAC1 and CDC42. BCR promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. BCR displays serine/threonine kinase activity. BCR catalyzes the reaction: ATP + a protein = ADP + a phosphoprotein. A chromosomal aberration involving BCR is a cause of chronic myeloid leukemia (CML). The antibody is specific to BCR.