BCR-Specific Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 19790-1-AP

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Freight/Packing

Con: 10 μg/150 μl

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Species specificity:
human

Recommended dilution:

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
breakpoint cluster region

Calculated molecular weight:
143 kDa

Observed molecular weight:

GenBank accession number:

Gene ID (NCBI):

Gene symbol
BCR

Synonyms
ALL, BCR, breakpoint cluster region, CML, D22S11, D22S662, FLJ16453, PHL
Background

BCR, also named as BCR1 and D22S11, is a GTPase-activating protein for RAC1 and CDC42. BCR promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. BCR displays serine/threonine kinase activity. BCR catalyzes the reaction: ATP + a protein = ADP + a phosphoprotein. A chromosomal aberration involving BCR is a cause of chronic myeloid leukemia (CML). The antibody is specific to BCR.


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