BRIP1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 20983-1-AP

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Freight/Packing

Con: 109 μg/150 μl

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Species specificity:
human

Positive WB detected in:
HeLa cells, Jurkat cells

Recommended dilution:
WB : 1:500-1:1000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
BRCA1 interacting protein C-terminal helicase 1

Calculated molecular weight:
141 kDa

Observed molecular weight:
141 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
BRIP1

Synonyms
BACH1, BRIP1, FANCJ, FLJ90232, OF
Background

BRIP1, also named as BACH1 and FANCJ, belongs to the DEAD box helicase family and DEAH subfamily. It is a DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. It is involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1. Defects in BRIP1 are a cause of susceptibility to breast cancer (BC). Defects in BRIP1 are the cause of Fanconi anemia complementation group J (FANCJ). The antibody is specific to BRIP1.


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