C9orf72 Antibody 7 Publications

Rabbit Polyclonal| Catalog number: 22637-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 39 μg/150 μl

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Species specificity:
human, mouse, rat, moouse

Positive WB detected in:
rat brain tissue, transfected cells, SH-SY5Y cells, HeLa cells, Sp2/0 cells, mouse testis tissue

Positive IP detected in:
SH-SY5Y cells

Positive IHC detected in:
human brain tissue, human gliomas tissue, human testis tissue

Positive IF detected in:
SH-SY5Y cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
chromosome 9 open reading frame 72

Calculated molecular weight:
481aa,54 kDa

Observed molecular weight:
50-54 kDa,25-30 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
C9orf72

Synonyms
C9orf72, C9RANT, RP11 27J8.2
Background

C9ORF72 has a domain whith polymorphic hexanucleotide repeat (GGGGCC). The C9ORF72-hexanucleotide repeat expansions have been recently identified as genetic markers in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). The C9ORF72 repeat expansions may indicate a worse prognosis in ALS. Human C9ORF72 has some isoforms with MW 54-60 kDa and 25-30 kDa. Mouse C9orf72 has some isoforms with MW 50-60 kDa and 35 kDa.


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