CBS Antibody 15 Publications

Rabbit Polyclonal| Catalog number: 14787-1-AP

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Freight/Packing

Con: 46 μg/150 μl

Choose size:

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Species specificity:
human, mouse, rat, Rabbit

Positive WB detected in:
mouse kidney tissue, HeLa cells, mouse brain tissue, mouse kidney tissue, rat brain tissue, rat liver tissue

Positive IP detected in:
mouse kidney tissue

Positive IHC detected in:
human pancreas cancer tissue, human colon tissue, human pancreas cancer tissue

Positive IF detected in:
Hela cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:100-1:400
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cystathionine-beta-synthase

Calculated molecular weight:
61 kDa

Observed molecular weight:
61 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CBS

Synonyms
Beta thionase, CBS, cystathionine beta synthase, HIP4, Serine sulfhydrase
Background

The CBS gene encodes cystathionine beta-synthase, which catalyzes the first irreversible step of transsulfuration. The CBS enzyme is a homotetramer of 63-kD subunits and requires pyridoxal phosphate and heme for activity(PMID:11230183). CBS protein is localized in most areas of the brain, but predominantly in the cell bodies and neuronal processes of Purkinje cells and Ammon's horn neurons(PMID:12588964).


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