CCAR2 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66497-1-Ig |CloneNo.: 2D10F8

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Freight/Packing

Con: 150 μg/150 μl

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Species specificity:
Human, pig

Positive WB detected in:
HeLa cells,pig brain tissue

Positive IHC detected in:
human cervical cancer tissue,human lung cancer tissue, human colon tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:2000-1:16000
IHC : 1:250-1:1000
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
KIAA1967

Calculated molecular weight:
923aa,103 kDa

Observed molecular weight:
130 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
KIAA1967

Synonyms
CCAR2, cell cycle and apoptosis regulator 2, DBC 1, DBC.1, DBC1, KIAA1967, p30 DBC, Protein KIAA1967
Background

Cell cycle and apoptosis regulator protein 2 (CCAR2), previously known as DBC1/KIAA1967, regulates diverse cellular functions including transcription, mRNA splicing, metabolism, and circadian cycle. CCAR2 is a critical regulator of cell death or survival following cellular stresses. CCAR2 is a widely expressed protein involved in the regulation of a variety of transcriptional complexes. High expression of CCAR2 correlates with poor outcomes in many human tumor types such as squamous cell carcinoma (SCC).


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