CD209 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 25404-1-AP

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Freight/Packing

Con: 35 μg/150 μl

Choose size:

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Species specificity:
human

Positive WB detected in:
human placenta tissue

Positive FC detected in:
U-937 cells

Recommended dilution:
WB : 1:500-1:2400

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
CD209 molecule

Calculated molecular weight:
404aa, 45.7 kDa

Observed molecular weight:
45 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CD209

Synonyms
CD209, CD209 antigen, CD209 molecule, CDSIGN, CLEC4L, DC SIGN, DC SIGN1
Background

CD209 (DC-SIGN, CLEC4L) is a C-type lectin receptor that is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens, including bacteria, viruses, and parasites. CD209 is preferentially expressed on dendritic cells (DCs). It mediates transient adhesion of DCs with T cells. It has been reported that CD209 plays a role in capture and transmission of HIV from DC to T cells (PMID: 10721995).


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