CIB1 Antibody 5 Publications

Rabbit Polyclonal| Catalog number: 11823-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 37 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human liver tissue, HepG2 cells, rat testis tissue

Positive IP detected in:
mouse testis tissue

Positive IHC detected in:
human breast cancer tissue, human testis tissue, rat testis tissue

Recommended dilution:
WB : 1:500-1:2400
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
calcium and integrin binding 1 (calmyrin)

Calculated molecular weight:
22 kDa

Observed molecular weight:
22 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CIB1

Synonyms
Calmyrin, CIB, CIB1, CIBP, DNA PKcs interacting protein, Kinase interacting protein, KIP, KIP1, PRKDCIP, SIP2 28, SNK interacting protein 2 28
Background

CIB1(Calcium and integrin-binding protein 1) is also named as CIB, KIP, PRKDCIP. It is an EF-hand-containing protein that binds multiple effector proteins, including the platelet αIIbβ3 integrin and several serine/threonine kinases and potentially modulates their function. It regulates platelet aggregation in hemostasis through a specific interaction with the alphaIIb cytoplasmic domain of platelet integrin alphaIIbbeta3.


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