Claudin 7 Polyclonal antibody
Claudin 7 Polyclonal Antibody for IHC, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse
Applications
WB, IF, IHC, ELISA
Conjugate
Unconjugated
Cat no : 10118-1-AP
Synonyms
Validation Data Gallery
Tested Applications
| Positive IHC detected in | human breast cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Recommended dilution
| Application | Dilution |
|---|---|
| Immunohistochemistry (IHC) | IHC : 1:200-1:800 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| IHC | See 1 publications below |
| IF | See 5 publications below |
Product Information
10118-1-AP targets Claudin 7 in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Cited Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Claudin 7 fusion protein Ag0159 |
| Full Name | claudin 7 |
| Calculated Molecular Weight | 22.4 kDa |
| Observed Molecular Weight | 23 kDa |
| GenBank Accession Number | BC001055 |
| Gene Symbol | CLDN7 |
| Gene ID (NCBI) | 1366 |
| RRID | AB_2083302 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
Claudins are a family of proteins that are the most important components of tight junctions, where they establish the paracellular barrier that controls the flow of molecules in the intercellular space between the cells of an epithelium. They are small (20-27 kilodalton (kDa)) proteins with very similar structures. They have four transmembrane domains, with the N-terminus and the C-terminus in the cytoplasm.
Protocols
| Product Specific Protocols | |
|---|---|
| IHC protocol for Claudin 7 antibody 10118-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Cancers (Basel) Targeting PVT1 Exon 9 Re-Expresses Claudin 4 Protein and Inhibits Migration by Claudin-Low Triple Negative Breast Cancer Cells. | ||
iScience Commercial dishes with gelatin-free microstructured inserts for elongated stem cell self-renewal and pluripotency | ||
Stem Cell Res Ther Human menstrual blood-derived stem cell transplantation suppresses liver injury in DDC-induced chronic cholestasis. | ||
FASEB J Steroid receptor coactivator-2 drives epithelial reprogramming that enables murine embryo implantation | ||
Front Pharmacol Berberine Improves Irinotecan-Induced Intestinal Mucositis Without Impairing the Anti-colorectal Cancer Efficacy of Irinotecan by Inhibiting Bacterial β-glucuronidase. | ||
Biol Reprod Pre-implantation triclosan exposure alters uterine receptivity through affecting tight junction protein†. |
