CNOT2 Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 10313-1-AP

Featured Product KD/KO validated

  • Print page
  • Download PDF

Be the first to review this product


-_-

Freight/Packing

Con: 20 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, rat

Positive WB detected in:
HEK-293 cells

Positive IF detected in:
HEK-293 cells

Recommended dilution:
WB : 1:200-1:1000
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
CCR4-NOT transcription complex, subunit 2

Calculated molecular weight:
60 kDa

Observed molecular weight:
60 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CNOT2

Synonyms
CCR4 associated factor 2, CDC36, CNOT2, FLJ26456, HSPC131, MSTP046, NOT2, NOT2H
Background

The Ccr4–Not complex is evolutionarily conserved and controls gene expression both at the level of transcription initiation and of mRNA degradation. And this complex can regulate pol II transcription. Promoter targeting of CCR4-NOT transcription complex subunit 2 (CNOT2) results in strong repression of pol II transcription. CNOT2-mediated repression is sensitive to the HDAC (histone deacetylase) inhibitor, TSA (trichostatin A).


Back
to top