Collagen Type VI Antibody 5 Publications

Rabbit Polyclonal| Catalog number: 17023-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human heart tissue, human skeletal muscle tissue

Positive IP detected in:
mouse heart tissue

Positive IHC detected in:
human kidney tissue, human placenta tissue, human heart tissue, human spleen tissue, human testis tissue, human skin tissue, human liver tissue, human ovary tissue, human lung tissue

Positive IF detected in:
mouse skeletal muscle tissue

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
collagen, type VI, alpha 1

Calculated molecular weight:
1028aa,109 kDa

Observed molecular weight:
140 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
COL6A1

Synonyms
COL6A1, collagen 6A1, Collagen alpha 1(VI) chain, collagen, type VI, alpha 1, OPLL
Background

Type VI Collagen is a major structural component of microfibrils. Type VI Collagen was found to be present throughout the connective tissue and in the extracellular matrix of cultured fibroblasts (PMID: 6723253). It is a heterotrimer composed of three different chains: alpha-1(VI), alpha-2(VI), and alpha-3(VI) or alpha-5(VI) or alpha-6(VI). The alpha-1(VI) chain is encoded by COL6A1 gene. Mutations in this gene result in Bethlem myopathy and Ullrich congenital muscular dystrophy.


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