DGKH Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 13873-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 45 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse brain tissue

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
human testis tissue

Positive IF detected in:
SH-SY5Y cells

Recommended dilution:
WB : 1:500-1:2400
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
diacylglycerol kinase, eta

Calculated molecular weight:
1100aa,122 kDa

Observed molecular weight:
135 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
DGKH

Synonyms
DAG kinase eta, DGK eta, DGKeta, DGKH, Diacylglycerol kinase eta, diacylglycerol kinase, eta, Diglyceride kinase eta, DKFZp761I1510
Background

DGKH(Diacylglycerol kinase eta) is also named as DGK-eta and belongs to the eukaryotic diacylglycerol kinase family. It is a key protein in the lithium-sensitive phosphatidyl inositol pathway, and more recently a link between environmental stress and schizophrenia and possibly bipolar disorder has been revealed. DGKH has 3 isoforms produced by alternative splicing.Two isoforms DGKH1 and DGKH2 with the molecular weight of 128 kDa and 135 kDa shows diacylglycerol kinase activity; however, the 2 isoforms differed in several other characteristics(PMID:12810723).


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