DLX4 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 12084-1-AP

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Con: 20 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human heart tissue

Positive IHC detected in:
human lymphoma

Positive IF detected in:
Hela

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
distal-less homeobox 4

Calculated molecular weight:
240aa,26 kDa

Observed molecular weight:
38kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
DLX4

Synonyms
DLX4, Homeobox protein DLX 4, Homeobox protein DLX 8, DLX8, BP1
Background

Globin genes' expression in the β-globin cluster is restricted to erythroid cells, with five different genes expressed during embryonic (e), fetal (Gγ and Aγ), and adult (δ and β) development [PMID:9461381]. Transcriptional activation of globin genes occurs not only by the binding of transcriptional activator proteins to the promoter of the gene being activated but also by a regulatory element located 6 to 18 kb upstream of the β-globin cluster, the locus control region (LCR)[PMID:8791532]. DXL4, also known as BP1, binds to two silencer DNA sequences upstream of the adult human β-globin gene and to a negative control region upstream of the adult δ-globin gene [PMID:11909945].


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