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  • KD/KO Validated

DRD2 Antibody

DRD2 Polyclonal Antibody for IHC, IP, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 55084-1-AP


D(2) dopamine receptor, D2DR, D2R, Dopamine D2 receptor, dopamine receptor D2, DRD2

Tested Applications

Positive IP detected inSH-SY5Y cells
Positive IHC detected inmouse brain tissue, human brain tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

Immunoprecipitation (IP)IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
Immunohistochemistry (IHC)IHC : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

55084-1-AP targets DRD2 in IP, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivity human, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name dopamine receptor D2
Calculated molecular weight 51 kDa
Observed molecular weight 51 kDa
GenBank accession number NM_016574
Gene symbol DRD2
Gene ID (NCBI) 1813
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Aliquoting is unnecessary for -20oC storage.

Background Information

DRD2, also named as D2DR and D2R, belongs to the G-protein coupled receptor 1 family. It is one of the five types (D1 to D5) of receptors for dopamine. The activity of DRD2 is mediated by G proteins which inhibit adenylyl cyclase. Defects in DRD2 are associated with dystonia type 11 (DYT11). The antibody is specific to DRD2.


Product Specific Protocols
IHC protocol for DRD2 antibody 55084-1-APDownload protocol
IP protocol for DRD2 antibody 55084-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols




Dopamine D2 receptors in the basolateral amygdala modulate erectile function in a rat model of nonorganic erectile dysfunction.

Authors - Guotao Chen

J Ethnopharmacol

The ancient Chinese formula Longdan Xiegan Tang improves antipsychotic-induced hyperprolactinemia by repairing the hypothalamic and pituitary TGF-β1 signaling in rats.

Authors - Liying Ren

J Ethnopharmacol

Paeoniflorin ameliorates antipsychotic-induced hyperprolactinemia in rats by attenuating impairment of the dopamine D2 receptor and TGF-β1 signaling pathways in the hypothalamus and pituitary.

Authors - Xiaoqian Huang

Mol Brain

Development of a peptide targeting dopamine transporter to improve ADHD-like deficits.

Authors - Terence K Y Lai

Mol Neurobiol

Protective Effect of Curcumin by Modulating BDNF/DARPP32/CREB in Arsenic-Induced Alterations in Dopaminergic Signaling in Rat Corpus Striatum.

Authors - Pranay Srivastava


Dopamine Controls Systemic Inflammation through Inhibition of NLRP3 Inflammasome.

Authors - Yiqing Yan
  • KD Validated


The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


Ping (Verified Customer) (06-04-2019)

This antibody is good for both immunoprecipitation and western blot.

  • Applications: Western Blot,Immunoprecipitation,
  • Primary Antibody Dilution: 1:500
  • Cell Tissue Type: rat brain tissue
No image submitted with review