DYNC1LI2 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 18885-1-AP

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Con: 26 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse colon tissue

Recommended dilution:
WB : 1:500-1:2000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
dynein, cytoplasmic 1, light intermediate chain 2

Calculated molecular weight:
492aa,54 kDa

Observed molecular weight:
60-65 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
DYNC1LI2

Synonyms
DNCLI2, DYNC1LI2, LIC 2, LIC2, LIC53/55
Background

Cytoplasmic dynein is a microtubule-associated motor protein. DYNC1LI2 (Cytoplasmic dynein 1 light intermediate chain 2), also known as LIC2, belongs to the dynein light intermediate chain family. DYNC1LI2 acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. It may play a role in binding dynein to membranous organelles or chromosomes. Northern blot analysis of rat tissues detected high expression of DYNC1LI2 in skeletal muscle, testis, heart, lung, and brain, and lower expression in liver, kidney, and spleen (PMID: 7738094).


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