FBX15 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 13024-1-AP

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Freight/Packing

Con: 31 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
A2780 cells, mouse ovary tissue

Recommended dilution:
WB : 1:500-1:3000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
F-box protein 15

Calculated molecular weight:
434aa,49 kDa

Observed molecular weight:
55kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
FBXO15

Synonyms
F box only protein 15, F box protein 15, FBX15, FBXO15
Background

F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins, and they are a family of eukaryotic proteins characterized by an approximately 40 amino acid motif. SCF complex, a class of ubiquitin ligases, consists of invariable components, Skp1 and Cullin, and variable components of F-box proteins, which have a primary role in determining substrate specificity. The F-box proteins are divided into 3 classes: FBWs containing WD-40 domains, FBLs containing leucine-rich repeats, and FBXs containing either different protein-protein interaction modules or no recognizable motifs. FBOX15 (or FBX15) belongs to the FBXs class, and 2 isoforms produced by alternative splicing has been described. This antibody is expected detect both isoforms.


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