|Positive WB detected in||U-937 cells|
|Positive FC detected in||K-562 cells|
|Western Blot (WB)||WB : 1:500-1:1000|
|Sample-dependent, check data in validation data gallery|
15625-1-AP targets FCGR2A / CD32a in WB, IF, FC, ELISA applications and shows reactivity with human samples.
|Cited Reactivity||human, rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||FCGR2A / CD32a fusion protein Ag8072|
|Full Name||Fc fragment of IgG, low affinity IIa, receptor (CD32)|
|Calculated molecular weight||35 kDa|
|Observed molecular weight||45 kDa|
|GenBank accession number||BC020823|
|Gene ID (NCBI)||2212|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
IgG Fc receptors (FcγRs) play important roles in immune responses. Low affinity IgG Fc receptor Fc gamma RIIa (FCGR2A, CD32a) is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes.
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