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  • KD/KO Validated

FOXL2-Specific Polyclonal antibody

FOXL2-Specific Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat and More (1)

Applications

WB, IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 19672-1-AP

Synonyms

BPES, BPES1, forkhead box L2, Forkhead box protein L2, FOXL2, FOXL2-Specific, PFRK, PINTO, POF3



Tested Applications

Positive WB detected inmouse ovary tissue, rat ovary tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

19672-1-AP targets FOXL2-Specific in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat, chicken
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name forkhead box L2
Calculated Molecular Weight 39 kDa
Observed Molecular Weight 49 kDa
GenBank Accession NumberNM_023067
Gene Symbol FOXL2
Gene ID (NCBI) 668
RRIDAB_2878594
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

FOXL2 is probable a transcriptional regulator. It is required to maintain the female phenotype throughout adulthood, and may provide clues to female infertility. Defects in FOXL2 are a cause of blepharophimosis, ptosis, and epicanthus inversus syndrome (BPES) Defects in FOXL2 are a cause of premature ovarian failure type 3 (POF3). This antibody is specific to the C-term of FOXL2.

Protocols

Product Specific Protocols
WB protocol for FOXL2-Specific antibody 19672-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB,IHC

Clin Cancer Res

HMGA2-FOXL2 Axis Regulates Metastases and Epithelial-to-mesenchymal Transition of Chemo-resistant Gastric Cancer.

Authors - Jiaqiang Dong
  • KD Validated
chickenIF

Aging (Albany NY)

Coherent apoptotic and autophagic activities involved in regression of chicken postovulatory follicles.

Authors - Xin Lin
ratIF,IHC

Stem Cell Res Ther

Concentrated exosomes from menstrual blood-derived stromal cells improves ovarian activity in a rat model of premature ovarian insufficiency.

Authors - Siwen Zhang
chickenIF

FASEB J

DMRT1 gene disruption alone induces incomplete gonad feminization in chicken.

Authors - Hong Jo Lee
ratIF

Chin Med

Neurobehavioral alternations of the female offspring born to polycystic ovary syndrome model rats administered by Chinese herbal medicine.

Authors - Xian Zhang
mouseIF

FASEB J

SP1 impacts the primordial to primary follicle transition by regulating cholesterol metabolism in granulosa cells

Authors - Jiaqi Zhou

Reviews

The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


FH

Y C (Verified Customer) (01-23-2020)

I use the free trial size antibody code from the 12 days of free X'mas gifts to order this.Free product and one figure!! Yay!

  • Applications: Western Blot,
  • Cell Tissue Type: 293T CELLS
FH

Kathryn (Verified Customer) (11-04-2019)

Image shows post-natal day 2 mouse ovary with germ cells marked by TRA98 (Abcam) in green and granulosa cells marked by FOXL2 (Proteintech) in red. This is an excellent granulosa cell marker.

  • Applications: Immunofluorescence,
  • Primary Antibody Dilution: 1:100
  • Cell Tissue Type: mouse ovary (granulosa cells)
FOXL2-Specific Antibody Immunofluorescence, validation (1:100 dilution) in mouse ovary (granulosa cells) (Cat no:19672-1-AP)