Ferritin light chain Antibody 11 Publications

Rabbit Polyclonal| Catalog number: 10727-1-AP

Featured Product KD/KO validated

  • Print page
  • Download PDF

-_-

Freight/Packing

Con: 52 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, rat, monkey

Positive WB detected in:
human placenta tissue, mouse brain tissue, mouse liver tissue, mouse ovary tissue, mouse spleen tissue

Positive IP detected in:
mouse liver tissue

Positive IHC detected in:
human liver cancer tissue, human liver tissue, human liver cancer tissue, human spleen tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:100-1:500
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
ferritin, light polypeptide

Calculated molecular weight:
19 kDa

Observed molecular weight:
20-22 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
FTL

Synonyms
Ferritin L subunit, Ferritin light chain, ferritin, light polypeptide, FTL
Background

FTL belongs to the ferritin family. It stores iron in a soluble, non-toxic, readily available form. FTL is important for iron homeostasis. It plays a role in delivery of iron to cells. FTL mediates iron uptake in capsule cells of the developing kidney. Mutation of FTL will cause hereditary hyperferritinemia-cataract syndrome (HHCS) or neurodegeneration with brain iron accumulation type 3 (NBIA3). Ferritin light polypeptide (FTL) and ferritin heavy polypeptide (FTH1) were the main constituents the striatum and cerebellar cortex revealed.


Back
to top