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CD42b Antibody 6 Publications

Rabbit Polyclonal| Catalog number: 12860-1-AP

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Con: 50 μg/150 μl

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Tested Applications

Applications:
WB, IHC, ELISA
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Images See all

CD42b Antibody WB Human peripheral blood platelets tissue 12860-1-AP

Human peripheral blood platelets were subjected to SDS PAGE followed by western blot with 12860-1-AP (CD42b antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours

CD42b Antibody IHC human spleen tissue 12860-1-AP

Immunohistochemical analysis of paraffin-embedded human spleen tissue slide using 12860-1-AP( CD42b antibody at dilution of 1:200 (under 10x lens).

CD42b Antibody IHC human spleen tissue 12860-1-AP

Immunohistochemical analysis of paraffin-embedded human spleen tissue slide using 12860-1-AP( CD42b antibody at dilution of 1:200 (under 40x lens).

Species specificity:
human, pig, mouse, rat
Positive WB detected in:
Human peripheral blood platelets, pig peripheral blood leukocyte, human blood
Positive IHC detected in:
human spleen tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Recommended dilution:
WB : 1:1000-1:8000
IHC : 1:50-1:500
Sample-dependent, check data in Validation tab

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
CD42b fusion protein Ag3893
Full name:
glycoprotein Ib (platelet), alpha polypeptide
Calculated molecular weight:
626aa,69 kDa
Observed molecular weight:
145 kDa
GenBank accession number:
BC027955
Gene ID (NCBI):
2811
Gene symbol
GP1BA
Synonyms
BSS, CD42b, CD42b alpha, GP1B, GP1BA

Background

GP1BA, also named as CD42b , is a 145-kDa surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium. It has a heterodimer form which composed of GP1BA and GP1BB.


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