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HNRNPA2B1 Antibody
HNRNPA2B1 Polyclonal Antibody for IF, IHC, IP, WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
IF, IHC, IP, WB, ELISA
Conjugate
Unconjugated
Cat no : 14813-1-AP
Synonyms
hnRNP A2/B1, HNRNPA2, HNRNPA2B1, HNRNPB1, HNRPA2, HNRPA2B1, HNRPB1, RNPA2, SNRPB1
Validation Data Gallery
Tested Applications
| Positive WB detected in | A431 cells, A549 cells, HeLa cells, HL-60 cells, Jurkat cells, K-562 cells, Raji cells |
| Positive IP detected in | mouse liver tissue |
| Positive IHC detected in | human lymphoma tissue, human cervical cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Positive IF detected in | HeLa cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:2000-1:16000 |
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Immunofluorescence (IF) | IF : 1:50-1:500 |
| Sample-dependent, check data in validation data gallery | |
Published Applications
| KD/KO | See 1 publications below |
| WB | See 5 publications below |
| IHC | See 2 publications below |
| IF | See 1 publications below |
Product Information
14813-1-AP targets HNRNPA2B1 in IF, IHC, IP, WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Reactivity | human, mouse, rat |
| Cited Species | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | HNRNPA2B1 fusion protein Ag6563 |
| Full Name | heterogeneous nuclear ribonucleoprotein A2/B1 |
| Calculated molecular weight | 37 kDa |
| Observed molecular weight | 36 kDa and 38 kDa |
| GenBank accession number | BC000506 |
| Gene symbol | HNRNPA2B1 |
| Gene ID (NCBI) | 3181 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20oC. Aliquoting is unnecessary for -20oC storage. |
Background Information
HnRNPA2B1 in one of heterogenous nuclear ribonucleoproteins (HnRNPs), which regulate the splicing and transportation of mRNA and participate in growth regulation and carcinogenesis. It has a role in packaging nascent mRNA, alternative splicing, tycoplamic RNA trafficking, translation and stabilization. Besides it may involve in telomere maintenance, cell proliferation and differentiation, and glucose transport. Gene HURNPA2B1 encode two protein, HNRNPA2 (38kd) and HNRNPB1 (36kd), by alternative splicing.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for HNRNPA2B1 antibody 14813-1-AP | Download protocol |
| IHC protocol for HNRNPA2B1 antibody 14813-1-AP | Download protocol |
| IF protocol for HNRNPA2B1 antibody 14813-1-AP | Download protocol |
| IP protocol for HNRNPA2B1 antibody 14813-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Med Sci Monit Expression and Prognostic Significance of m6A-Related Genes in Lung Adenocarcinoma. | ||
PLoS One HnRNP A1/A2 and SF2/ASF regulate alternative splicing of interferon regulatory factor-3 and affect immunomodulatory functions in human non-small cell lung cancer cells.
| ||
ACS Chem Neurosci Targeting the Cyclophilin Domain of Ran-binding Protein 2 (Ranbp2) with Novel Small Molecules to Control the Proteostasis of STAT3, hnRNPA2B1 and M-Opsin. | ||
J Biol Chem Differential Loss of Prolyl-Isomerase or Chaperone Activity of Ran-binding protein 2 (Ranbp2) Unveils Distinct Physiological Roles of Its Cyclophilin Domain in Proteostasis. | ||
Oncogene The homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis. |
