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HNRNPA2B1 Antibody

HNRNPA2B1 Polyclonal Antibody for IF, IHC, IP, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IF, IHC, IP, WB, ELISA

Conjugate

Unconjugated

Cat no : 14813-1-AP

Synonyms

hnRNP A2/B1, HNRNPA2, HNRNPA2B1, HNRNPB1, HNRPA2, HNRPA2B1, HNRPB1, RNPA2, SNRPB1



Tested Applications

Positive WB detected inA431 cells, A549 cells, HeLa cells, HL-60 cells, Jurkat cells, K-562 cells, Raji cells
Positive IP detected inmouse liver tissue
Positive IHC detected inhuman lymphoma tissue, human cervical cancer tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inHeLa cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:2000-1:16000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

14813-1-AP targets HNRNPA2B1 in IF, IHC, IP, WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Reactivity human, mouse, rat
Cited Species human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen HNRNPA2B1 fusion protein Ag6563
Full Name heterogeneous nuclear ribonucleoprotein A2/B1
Calculated molecular weight 37 kDa
Observed molecular weight 36 kDa and 38 kDa
GenBank accession number BC000506
Gene symbol HNRNPA2B1
Gene ID (NCBI) 3181
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20oC. Aliquoting is unnecessary for -20oC storage.

Background Information

HnRNPA2B1 in one of heterogenous nuclear ribonucleoproteins (HnRNPs), which regulate the splicing and transportation of mRNA and participate in growth regulation and carcinogenesis. It has a role in packaging nascent mRNA, alternative splicing, tycoplamic RNA trafficking, translation and stabilization. Besides it may involve in telomere maintenance, cell proliferation and differentiation, and glucose transport. Gene HURNPA2B1 encode two protein, HNRNPA2 (38kd) and HNRNPB1 (36kd), by alternative splicing.

Protocols

Product Specific Protocols
WB protocol for HNRNPA2B1 antibody 14813-1-APDownload protocol
IHC protocol for HNRNPA2B1 antibody 14813-1-APDownload protocol
IF protocol for HNRNPA2B1 antibody 14813-1-APDownload protocol
IP protocol for HNRNPA2B1 antibody 14813-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanIHC

Med Sci Monit

Expression and Prognostic Significance of m6A-Related Genes in Lung Adenocarcinoma.

Authors - Yingying Zhang

Scand J Immunol

Bioinformatics driven new immune target discovery in disease.

Authors - Chunhe Yang
humanWB,IHC

PLoS One

HnRNP A1/A2 and SF2/ASF regulate alternative splicing of interferon regulatory factor-3 and affect immunomodulatory functions in human non-small cell lung cancer cells.

Authors - Guo Rong R
  • KD Validated
humanWB

ACS Chem Neurosci

Targeting the Cyclophilin Domain of Ran-binding Protein 2 (Ranbp2) with Novel Small Molecules to Control the Proteostasis of STAT3, hnRNPA2B1 and M-Opsin.

Authors - Kyoungin Cho
mouseWB,IF

J Biol Chem

Differential Loss of Prolyl-Isomerase or Chaperone Activity of Ran-binding protein 2 (Ranbp2) Unveils Distinct Physiological Roles of Its Cyclophilin Domain in Proteostasis.

Authors - Kyoung-In Cho
humanWB

Oncogene

The homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis.

Authors - Tianliang He