IKBKB Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 20979-1-AP

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Freight/Packing

Con: 60 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse testis tissue

Positive IHC detected in:
human breast cancer tissue, human breast cancer tissue, human pancreas tissue

Positive IF detected in:
DU 145 cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:100-1:400
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta

Calculated molecular weight:
87 kDa

Observed molecular weight:
85 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IKBKB

Synonyms
FLJ40509, I kappa B kinase 2, I kappa B kinase beta, IKBKB, IKK B, IKK beta, IKK2, IKKB, NFKBIKB
Background

IKBKB, also named as NFKBIKB, IKK2 and IKKB, belongs to the protein kinase superfamily, Ser/Thr protein kinase family and I-kappa-B kinase subfamily. IKBKB acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. It also phosphorylates NCOA3. The antibody is specific to IKBKB.


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