NeutraKine™ IL-4 Monoclonal antibody
NeutraKine™ IL-4 Monoclonal Antibody for Neutralization,ELISA
Host / Isotype
Mouse / IgG1
Cat no : 69005-1-Ig
|Neutralization||Measured by its ability to neutralize Human IL-4 induced proliferation of TF-1 cell line (human erythroleukemic cell line). The half neutralization dose (ND50) is typically 200-500 ng/mL in the presence of 0.5 ng/mL human IL-4.|
69005-1-Ig targets NeutraKine™ IL-4 in Neutralization,ELISA applications and shows reactivity with Human samples.
|Host / Isotype||Mouse / IgG1|
|Immunogen||human Humankine IL-4 protein HZ-1004|
|Full Name||interleukin 4|
|Gene ID (NCBI)||3565|
|Purification Method||Protein G purification|
|Storage Buffer||Sterile PBS.|
|Reconstitution||This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use.|
|Stability and Storage||Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.|
IL4 is a cytokine produced by CD4+ T cells in response to helminthes and other extracellular parasites. It promotes the proliferation and differentiation of antigen presenting cells. IL4 also plays a pivotal role in antibody isotype switching and stimulates the production of IgE. This cytokine has been applied in the treatment of autoimmune disorder like multiple myeloma, cancer, psoriasis, and arthritis. IL4 has also been extensively applied to inhibit detrimental effect of Th1. It may promote the growth of epithelial tumors by mediating increased proliferation and survival.
This antibody is used to Block/Neutralize IL4 protein.