IL1 beta Antibody
IL1 beta Polyclonal Antibody for WB, ELISA
Cat no : 16806-1-AP
IL1 beta, Catabolin, IL 1, IL 1 beta, IL1 BETA, IL-1 beta, IL1B, IL1beta, IL1F2, IL-1β, Interleukin 1 beta, interleukin 1, beta, Pro IL-1β
|Positive WB detected in||THP-1 cells, A431 cells, human adrenal gland tissue|
|Western Blot (WB)||WB : 1:500-1:2000|
|Sample-dependent, check data in validation data gallery|
The 16806-1-AP immunogen is Fusion Protein IL1 beta protein expressed in E. coli.
|Cited Species||human, zebrafish|
|Host / Isotype||Rabbit / IgG|
|Immunogen||IL1 beta fusion protein Ag10295|
|Full Name||interleukin 1, beta|
|Calculated molecular weight||269aa,31 kDa|
|Observed molecular weight||30-35 kDa|
|GenBank accession number||BC008678|
|Gene ID (NCBI)||3553|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20oC. Aliquoting is unnecessary for -20oC storage.|
Interleukin-1, produced mainly by blood monocytes, mediates the panoply of host reactions collectively known as acute phase response. It is identical to endogenous pyrogen. The multiple biologic activities that define IL1 are properties of a 15- to 18-kD protein that is derived from a 30- to 35-kD precursor. Interleukin 1β (IL-1B) is a member of the interleukin 1 cytokine family. It is a pro-inflammatory cytokine against infection, playing an important role in the pathogenesis of cancers. It signals through various adaptor proteins and kinases that lead to activation of numerous downstream targets. The expression level of IL-1B is very low.
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