IL1 beta Antibody 30 Publications

Rabbit Polyclonal| Catalog number: 16806-1-AP

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Freight/Packing

Con: 29 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
A431 cells, Transfected HEK-293 cells

Positive IHC detected in:
human skin tissue, human heart tissue, human kidney tissue, human lung tissue, human ovary tissue, human placenta tissue, human skin tissue, human testis tissue, human tonsillitis tissue, mouse heart tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:50-1:500
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
interleukin 1, beta

Calculated molecular weight:
269aa,31 kDa

Observed molecular weight:
30-35 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
IL1B

Synonyms
IL1 beta, Catabolin, IL 1, IL 1 beta, IL1 BETA, IL1B, IL1beta, IL1F2, IL-1β, Interleukin 1 beta, interleukin 1, beta
Background

Interleukin-1, produced mainly by blood monocytes, mediates the panoply of host reactions collectively known as acute phase response. It is identical to endogenous pyrogen. The multiple biologic activities that define IL1 are properties of a 15- to 18-kD protein that is derived from a 30- to 35-kD precursor. Interleukin 1β (IL-1B) is a member of the interleukin 1 cytokine family. It is a pro-inflammatory cytokine against infection, playing an important role in the pathogenesis of cancers. It signals through various adaptor proteins and kinases that lead to activation of numerous downstream targets. The expression level of IL-1B is very low.


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