CD11c/Integrin alpha X Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 17342-1-AP

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Freight/Packing

Con: 30 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human blood tissue

Positive IHC detected in:
human tonsillitis tissue,human spleen tissue

Positive FC detected in:
HL-60 cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
integrin, alpha X (complement component 3 receptor 4 subunit)

Calculated molecular weight:
1169aa,129 kDa

Observed molecular weight:
150 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ITGAX

Synonyms
CD11C, Integrin alpha X, ITGAX, Leu M5, SLEB6
Background

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits. CD11c/Integrin alpha X is a 145-150 kDa type I transmembrane glycoprotein present on a variety of cells, including monocytes/macrophages, granulocytes, NK cells and dendritic cells. Integrin alpha X/beta 2 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis.


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