|Positive WB detected in||human blood tissue|
|Positive IHC detected in||human tonsillitis tissue, mouse spleen tissue, human spleen tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Positive FC detected in||HL-60 cells|
|Western Blot (WB)||WB : 1:500-1:1000|
|Immunohistochemistry (IHC)||IHC : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
17342-1-AP targets CD11c/Integrin Alpha X in WB, IHC, IF, FC,ELISA applications and shows reactivity with human, mouse samples.
|Tested Reactivity||human, mouse|
|Cited Reactivity||human, mouse, pig|
|Host / Isotype||Rabbit / IgG|
|Immunogen||CD11c/Integrin Alpha X fusion protein Ag11380|
|Full Name||integrin, alpha X (complement component 3 receptor 4 subunit)|
|Calculated molecular weight||1169 aa, 129 kDa|
|Observed molecular weight||150 kDa|
|GenBank accession number||BC038237|
|Gene ID (NCBI)||3687|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits. CD11c/Integrin alpha X is a 145-150 kDa type I transmembrane glycoprotein present on a variety of cells, including monocytes/macrophages, granulocytes, NK cells and dendritic cells. Integrin alpha X/beta 2 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis.
|Product Specific Protocols|
|WB protocol for CD11c/Integrin Alpha X antibody 17342-1-AP||Download protocol|
|IHC protocol for CD11c/Integrin Alpha X antibody 17342-1-AP||Download protocol|
|FC protocol for CD11c/Integrin Alpha X antibody 17342-1-AP||Download protocol|
|Click here to view our Standard Protocols|
Protective Effects of Live Combined B. subtilis and E. faecium in Polymicrobial Sepsis Through Modulating Activation and Transformation of Macrophages and Mast Cells.
J Cell Mol Med
PTPN2 improved renal injury and fibrosis by suppressing STAT-induced inflammation in early diabetic nephropathy.
J Diabetes Res
Attenuation of Diabetic Nephropathy in Diabetic Mice by Fasudil through Regulation of Macrophage Polarization.
Asia Pac Allergy
CD11c(+) dendritic cells coexpressing thymic stromal lymphopoietin receptor in animal model of eosinophilic otitis media.
(+)-Borneol improves the efficacy of edaravone against DSS-induced colitis by promoting M2 macrophages polarization via JAK2-STAT3 signaling pathway.
Eur J Gastroenterol Hepatol
Indoleamine 2,3-dioxygenase expression in human inflammatory bowel disease.