Eg5 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 23333-1-AP

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Freight/Packing

Con: 35 μg/150 μl

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Species specificity:
human

Positive WB detected in:
PC-13 cells, HEK-293 cells, MCF-7 cells, Raji cells

Positive IP detected in:
Raji cells

Positive IHC detected in:
human lung cancer tissue, human prostate hyperplasia tissue

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen Affinity purified

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
kinesin family member 11

Calculated molecular weight:
1056aa,119 kDa

Observed molecular weight:
120-130 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
KIF11

Synonyms
EG5, HKSP, KIF11, kinesin family member 11, Kinesin like protein 1, Kinesin like protein KIF11, KNSL1, TR interacting protein 5, TRIP 5, TRIP5
Background

Eg5 is a plus-end-directed microtubule motor encoded by KIF11 gene. It is an essential mitotic kinesin that plays a pivotal role in the formation and maintenance of bipolar spindle during early prometaphase. Eg5 has been implicated in tumourigenesis, and its overexpression has been found in various cancer tissues.


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