|Positive WB detected in||Jurkat cells, HEK-293 cells, human liver tissue|
|Western Blot (WB)||WB : 1:500-1:1000|
|Sample-dependent, check data in validation data gallery|
10935-1-AP targets NKG2A in WB, ELISA applications and shows reactivity with human samples.
|Host / Isotype||Rabbit / IgG|
|Immunogen||NKG2A fusion protein Ag1376|
|Full Name||killer cell lectin-like receptor subfamily C, member 1|
|Calculated molecular weight||26 kDa|
|Observed molecular weight||33 kDa|
|GenBank accession number||BC012550|
|Gene ID (NCBI)||3821|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.1% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20oC. Aliquoting is unnecessary for -20oC storage.|
KLRC1, also known as NKG2A (NKG2) and CD159A, is a single-pass type II membrane protein with extracellular C-type lectin domain. It belongs to the natural killer cell lectin-like receptor family, which is a group of transmembrane proteins preferentially expressed in NK cells. KLRC1 can form a heterodimer with CD94. The NKG2A/CD94 complex is an inhibitory receptor that recognizes HLA-E and is expressed by NK cells and a subset of T cells.