NKG2A Antibody

NKG2A Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 10935-1-AP

Synonyms

CD159A, KLRC1, NK cell receptor A, NKG2, NKG2A



Tested Applications

Positive WB detected inJurkat cells, HEK-293 cells, human liver tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Sample-dependent, check data in validation data gallery

Product Information

10935-1-AP targets NKG2A in WB, ELISA applications and shows reactivity with human samples.

Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen NKG2A fusion protein Ag1376
Full Name killer cell lectin-like receptor subfamily C, member 1
Calculated molecular weight 26 kDa
Observed molecular weight 33 kDa
GenBank accession number BC012550
Gene symbol KLRC1
Gene ID (NCBI) 3821
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20oC. Aliquoting is unnecessary for -20oC storage.

Background Information

KLRC1, also known as NKG2A (NKG2) and CD159A, is a single-pass type II membrane protein with extracellular C-type lectin domain. It belongs to the natural killer cell lectin-like receptor family, which is a group of transmembrane proteins preferentially expressed in NK cells. KLRC1 can form a heterodimer with CD94. The NKG2A/CD94 complex is an inhibitory receptor that recognizes HLA-E and is expressed by NK cells and a subset of T cells.

Protocols

Product Specific Protocols
WB protocol for NKG2A antibody 10935-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle

PLoS One

Flow Cytometric Immunophenotyping Is Sensitive for the Early Diagnosis of De Novo Aggressive Natural Killer Cell Leukemia (ANKL): A Multicenter Retrospective Analysis.

Authors - Yi Li