Cytokeratin 7-specific Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 16857-1-AP

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Freight/Packing

Con: 27 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse liver tissue, HepG2 cells

Positive IP detected in:
mouse liver tissue

Positive IHC detected in:
human placenta tissue, human breast cancer tissue, human heart tissue, human liver tissue, human lung cancer tissue, human spleen tissue, human stomach cancer tissue, human testis tissue, mouse lung tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
keratin 7

Calculated molecular weight:
51 kDa

Observed molecular weight:
54 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
KRT7

Synonyms
CK 7, CK7, Cytokeratin 7, K2C7, K7, keratin 7, KRT7, Sarcolectin, SCL, Type II keratin Kb7
Background

Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT7, also named as cytokeratin 7, is one member of type II basic cytokeratin. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels, and their neoplasms. KRT7 is marker of epithelial tissues, but not present in carcinomas of stratified squamous cell origin.This antibody is specifically against KRT7.


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