LGR5 Polyclonal Antibody for IHC, ELISA
Cat no : 21833-1-AP
FEX, G protein coupled receptor 49, G protein coupled receptor 67, GPR49, GPR67, GRP49, HG38, LGR5
|Positive IHC detected in||human small intestine tissue, human colon tissue, human colon cancer tissue, human liver cancer tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Immunohistochemistry (IHC)||IHC : 1:100-1:400|
|Sample-dependent, check data in validation data gallery|
The 21833-1-AP immunogen is Fusion Protein LGR5 protein expressed in E. coli.
|Host / Isotype||Rabbit / IgG|
|Immunogen||LGR5 fusion protein Ag16389|
|Full Name||leucine-rich repeat-containing G protein-coupled receptor 5|
|Calculated molecular weight||907aa,100 kDa|
|Observed molecular weight|
|GenBank accession number||BC096324|
|Gene ID (NCBI)||8549|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
LGR5, also named as GPR49, GPR67 and HG38, belongs to the G-protein coupled receptor 1 family. It is an orphan receptor. LGR5 is a stem cell marker of the intestinal epithelium and the hair follicule. It is a target gene of Wnt signaling.
Expression and clinical significance of SALL4 and LGR5 in patients with lung cancer.
Detection of circulating colorectal cancer cells by a custom microfluid system before and after endoscopic metallic stent placement.
Correlation of Musashi-1, Lgr5, and pEGFR expressions in human small intestinal adenocarcinomas.
LGR5 regulates pro-survival MEK/ERK and proliferative Wnt/β-catenin signalling in neuroblastoma.