LINGO1 Polyclonal antibody

LINGO1 Polyclonal Antibody for FC, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, FC, ELISA

Conjugate

Unconjugated

Cat no : 19097-1-AP

Synonyms

LERN1, LINGO1, LRRN6A, UNQ201



Tested Applications

Positive WB detected inmouse brain tissue, rat brain tissue
Positive FC detected inSH-SY5Y cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Sample-dependent, check data in validation data gallery

Product Information

The immunogen of 19097-1-AP is LINGO1 Fusion Protein expressed in E. coli.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen LINGO1 fusion protein Ag13553
Full Name leucine rich repeat and Ig domain containing 1
Calculated molecular weight 70 kDa
Observed molecular weight 83 kDa
GenBank accession numberBC011057
Gene symbol LINGO1
Gene ID (NCBI) 84894
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

LINGO-1 is a transmembrane receptor that contains 12 leucine-rich repeats and an immunoglobulin domain. It is expressed primarily in the central nervous system. LINGO-1 binds Nogo-66 receptor (NgR) and p75 and that is a functional component of the NgR/p75 signaling complex (PMID: 14966521). This protein has a calculated molecular weight of 70 kDa and migrates at higher molecular weight due to glycosylation (PMID: 21872576; 25257685; 18326721).

Protocols

Product Specific Protocols
WB protocol for LINGO1 antibody 19097-1-APDownload protocol
FC protocol for LINGO1 antibody 19097-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols