MAP2 Antibody 24 Publications

Rabbit Polyclonal| Catalog number: 17490-1-AP

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Freight/Packing

Con: 39 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
SH-SY5Y cells, mouse brain tissue

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
human brain tissue, human brain tissue, mouse brain tissue, rat brain tissue

Positive IF detected in:
mouse brain tissue

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:400
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
microtubule-associated protein 2

Calculated molecular weight:
200 kDa

Observed molecular weight:
280 kDa, 70-85 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
MAP2

Synonyms
DKFZp686I2148, MAP 2, MAP2, MAP2A, MAP2B, MAP2C
Background

MAP2 (microtubule-associated protein 2) is a cytoskeleton protein abundant in brain and has important role in neuronal morphogenesis. Multiple high molecular weight (MW) and low molecular weight (MW) MAP2 isoforms are expressed within axons, dendrites, and cell bodies. The expression of MAP2 is regulated in both a tissue- and developmentally specific manner. The 280 kD MAP2B is present throughout rat brain development, and the slightly larger MAP2A appears first during the end of the second week of postnatal life. MAP2C, composed of several bands of about 70 kD, is present during early brain development, and largely disappears from the mature brain except for the retina, olfactory bulb, and cerebellum. MAP2 antibodies have been widely used to mark the neuron or dendrite formation. This antibody can recognize both high MW and low MW isoforms of MAP2.


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