MAT1A Antibody 5 Publications

Rabbit Polyclonal| Catalog number: 12395-1-AP

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Con: 23 μg/150 μl

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Species specificity:
human, mouse, rat, arabidopsis

Positive WB detected in:
mouse liver tissue, arabidopsis whole plant

Positive IHC detected in:
human lung tissue

Recommended dilution:
WB : 1:1000-1:4000
IHC : 1:20-1:400

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
methionine adenosyltransferase I, alpha

Calculated molecular weight:
395aa,44 kDa

Observed molecular weight:
44-55 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
MAT1A

Synonyms
AdoMet synthase 1, AMS1, MAT, MAT 1, MAT I/III, MAT1A, MATA1, SAMS, SAMS1
Background

Methionine adenosyltransferase (MAT) is the enzyme that catalyzes the synthesis of S-adeno-sylmethionine (AdoMet), the main donor of methyl groups in the cell. In mammals MAT is encoded by two different genes, MAT1A and MAT2A. MAT1A is expressed only in the mature liver whereas fetal hepatocytes, extrahepatic tissues and liver cancer cells express MAT2A. This antibody was raised against the full length of human MAT1A and may cross-react with MAT2A. Western blot analysis using this antibody detected a single band around 44-50kD in liver.


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