MRP2 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 24893-1-AP

  • Print page
  • Download PDF

-_-

Freight/Packing

Con: 34 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse

Positive WB detected in:
HepG2 cells, mouse kidney tissue

Positive IHC detected in:
human small intestine tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
ATP-binding cassette, sub-family C (CFTR/MRP), member 2

Calculated molecular weight:
1545aa,174 kDa

Observed molecular weight:
190-250 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ABCC2

Synonyms
ABC30, ABCC2, MRP2
Background

Multi-drug resistance protein 2 (MRP2), also known as ABCC2, is an ATP binding cassette (ABC) transporter responsible for biliary excretion of xenobiotics, endobiotics, and their metabolites. Deficiency in ABCC2 results in the clinical disorder Dubin-Johnson syndrome. MRP2 is found to be expressed in a variety of human cancers, and is associated with resistance of tumor cells to various anticancer drugs including cisplatin. The predicted molecular weight of MRP2 is 174 kDa, while mature MRP2 usually has a slower migration around 190-250 kDa due to the glycosylation. (16434545, 18834541, 23045960)


Back
to top