Back

NOD2 Antibody 9 Publications

Rabbit Polyclonal| Catalog number: 20980-1-AP

  • Print page
  • Download PDF

Be the first to review this product

-_-

Freight/Packing

Con: 53 μg/150 μl

Choose size:

Please visit your regions distributor:

Request quote for
bulk/custom formulations

Related Primary Antibodies
Special offer: Add control/tag antibody for $99
Load more

Tested Applications

Applications:
WB, IHC, IF, ELISA
Application not tested? Please see our Guarantee


Images See all

NOD2 Antibody WB Jurkat cells 20980-1-AP

Jurkat cells were subjected to SDS PAGE followed by western blot with 20980-1-AP(NOD2 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours

NOD2 Antibody IF HeLa cells 20980-1-AP

Immunofluorescent analysis of ( -20°C Ethanol) fixed HeLa cells using 20980-1-AP (NOD2 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L)

NOD2 Antibody IHC human colon tissue 20980-1-AP

Immunohistochemistry of paraffin-embedded human colon tissue slide using 20980-1-AP( NOD2 antibody) at dilution of 1:200 (under 10x lens).

NOD2 Antibody IHC human colon tissue 20980-1-AP

Immunohistochemistry of paraffin-embedded human colon tissue slide using 20980-1-AP( NOD2 antibody) at dilution of 1:200 (under 40x lens).

Species specificity:
human, mouse, cow, rat
Positive WB detected in:
Jurkat cells
Positive IHC detected in:
human colon tissue
Positive IF detected in:
HeLa cells
Recommended dilution:
WB : 1:500-1:1000
IHC : 1:50-1:500
IF : 1:50-1:500

Protocols

Product-specific protocols

Standard Protocols

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
Peptide
Full name:
nucleotide-binding oligomerization domain containing 2
Calculated molecular weight:
115 kDa
Observed molecular weight:
115 kDa
GenBank accession number:
NM_022162
Gene ID (NCBI):
64127
Gene symbol
NOD2
Synonyms
ACUG, BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, NOD2, NOD2B, PSORAS1

Background

NOD2, also named as CARD15 and IBD1, induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK-gamma. It confers responsiveness to intracellular bacterial lipopolysaccharides (LPS). Defects in NOD2 are the cause of Blau syndrome (BS). Defects in NOD2 are a cause of susceptibility to Crohn disease (CD). Defects in NOD2 are a cause of susceptibility to ulcerative colitis. Defects in NOD2 are the cause of early-onset sarcoidosis (EOS). The antibody is specific to NOD2.


Back
to top