NONO Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66361-1-Ig |CloneNo.: 2A2B10

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Freight/Packing

Con: 150 μg/150 μl

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Species specificity:
human, rat, mouse

Positive WB detected in:
C2C12 cell, mouse skeletal muscle tissue, ROS1728 cells

Recommended dilution:
WB : 1:500-1:2000

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
non-POU domain containing, octamer-binding

Calculated molecular weight:
54 kDa

Observed molecular weight:
54 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
NONO

Synonyms
55 kDa nuclear protein, NONO, NonO protein, NRB54, P54, p54(nrb), P54NRB
Background

Non-pou domain-containing octamer-binding protein(NONO), other named p54nrb, belongs to DBHS family, whose protein are predominately nuclear and involves in transcriptional and posttranscriptional gene regulatory functions as well as DNA repair. This family has roles in a wide range of biological processes, such as the regulation of circadian rhythm, carcinogenesis and progression of cancer. NONO forms heterodimer with SFPQ, and has been implicated in nuclear retention of A- to I-edited RNA as paraspeckle components, pre-mRAN 3'-end formation, cAMP cycling and transcriptional activation.


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