- Featured Product
- KD/KO Validated
NRF1/nuclear respiratory factor 1 Antibody
NRF1/nuclear respiratory factor 1 Polyclonal Antibody for WB, ELISA
Cat no : 12482-1-AP
ALPHA PAL, NRF 1, NRF1, NRF1/nuclear respiratory factor 1, nuclear respiratory factor 1
|Positive WB detected in||A549 cells, human lung tissue, A431 cells|
|Western Blot (WB)||WB : 1:500-1:3000|
|Sample-dependent, check data in validation data gallery|
12482-1-AP targets NRF1/nuclear respiratory factor 1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||chicken, goat, human, mouse, rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||NRF1/nuclear respiratory factor 1 fusion protein Ag3172|
|Full Name||nuclear respiratory factor 1|
|Calculated molecular weight||522aa,56 kDa|
|Observed molecular weight||67 kDa, 45 kDa|
|GenBank accession number||BC016925|
|Gene ID (NCBI)||4899|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
NRF1, also named as Alpha-pal and NRF-1, belongs to the NRF1/Ewg family. It is a transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. NRF1 is implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. It plays a critical role in regulating the expression of many antioxidant response element (ARE)-dependent genes. NRF1 exists various isoforms and long isoform is about 67 kDa and short isoform is about 45 kDa.
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