PARL Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 26679-1-AP

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Freight/Packing

Con: 70 μg/150 μl

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Species specificity:
human

Positive WB detected in:
3T3-L1 cells, HEK-293 cells, HeLa cells, Neuro-2a cells

Positive IHC detected in:
human prostate cancer tissue, human liver cancer tissue, human prostate cancer tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
presenilin associated, rhomboid-like

Calculated molecular weight:
42 kDa

Observed molecular weight:
42 kDa,45 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PARL

Synonyms
PARL, Pbeta, PRO2207, PSARL, PSARL1, PSENIP2, RHBDS1
Background

Presenilin associated rhomboid like(PARL), is a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. PARL has 2 isoforms produced by alternative splicing. PARL regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of PARL may result in the release of a small peptide, P-beta, which may transit to the nucleus.


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