PAX8-Specific Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66073-1-Ig |CloneNo.: 2H9E1

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Freight/Packing

Con: 113 μg/150 μl

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Species specificity:
human

Positive WB detected in:
Skov-3 cells

Positive IHC detected in:
human thyroid tissue, human ovary tumor tissue, human thyroid tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2b

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
paired box 8

Calculated molecular weight:
48 kDa

Observed molecular weight:
48kD

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PAX8

Synonyms
paired box 8, Paired box protein Pax 8, PAX8
Background

PAX8 is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain and a paired-type homeodomain. The specific function of the PAX8 is unknown but it may involve kidney cell differentiation, thyroid development, or thyroid dysgenesis. Several other splice variants have been proposed but the full nature of these products has not been described. Pax8 is also a marker of otic progenitor cells. Mutation of PAX8 will cause congenital hypothyroidism non-goitrous type 2 (CHNG2). This antibody is specific to Pax8. It will not cross react with other PAX members


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