PDK1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 18262-1-AP

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Freight/Packing

Con: 40 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse liver tissue, HEK-293 cells, mouse liver tissue, NIH/3T3 cells, rat kidney tissue

Positive IHC detected in:
human heart tissue

Positive IF detected in:
HEK-293 cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
pyruvate dehydrogenase kinase, isozyme 1

Calculated molecular weight:
436aa,49 kDa

Observed molecular weight:
49 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
PDK1

Synonyms
PDH kinase 1, PDHK1, PDK1, Pyruvate dehydrogenase kinase isoform 1
Background

PDK1(pyruvate dehydrogenase kinase isoform 1) is also named as PDHK1 and belongs to the PDK/BCKDK protein kinase family.It inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism(PMID:17683942).Starvation increases islet PDK activity(PMID:11723055).This antibody is speicfic to PDK1.


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