Tested Applications
| Positive WB detected in | 5637 cells, HEK-293 cells, Karpas-299 cells, Raji cells, SCaBER cells, U-251 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
17418-1-AP targets Noxa in WB, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag11387 Product name: Recombinant human NOXA protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-136 aa of BC032663 Sequence: MPGKKARKNAQPSPARAPAGPAGTAGTARDQAGFAIGMQLRFTRGKKLLSSSLSSSPLALPRGHEEQVQVAGSRVCYSTQEIWRQTELPAETSESDIQTLLLRNLTASKTCMRGLLQKSFLRRCTFHQFEERLHCN Predict reactive species |
| Full Name | phorbol-12-myristate-13-acetate-induced protein 1 |
| Calculated Molecular Weight | 136 aa, 15 kDa |
| Observed Molecular Weight | 6-15 kDa |
| GenBank Accession Number | BC032663 |
| Gene Symbol | NOXA |
| Gene ID (NCBI) | 5366 |
| RRID | AB_3669271 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q13794 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for Noxa antibody 17418-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
What published studies show
The Noxa Polyclonal antibody (Cat# 17418-1-AP) has 4 total citations. These appear in International Journal of Molecular Sciences, Targeted Oncology, Naunyn-Schmiedeberg's Archives of Pharmacology, and Cancer Medicine. The associated research fields include esophageal squamous cell carcinoma, acute myeloid leukemia, glioma, and colon cancer, with studies focusing on apoptosis, ubiquitin-mediated degradation, and antitumor drug synergy.
| Species | Application | Title |
|---|---|---|
Int J Mol Sci Deferasirox Targets TAOK1 to Induce p53-Mediated Apoptosis in Esophageal Squamous Cell Carcinoma | ||
Target Oncol Venetoclax Synergistically Enhances the Anti-leukemic Activity of Vosaroxin Against Acute Myeloid Leukemia Cells Ex Vivo. | ||
Naunyn Schmiedebergs Arch Pharmacol Plitidepsin induces apoptosis in glioma cells through β-TrCP-mediated ubiquitination and degradation of BMI1. | ||
Cancer Med In vitro additive antitumor effects of dimethoxycurcumin and 5-fluorouracil in colon cancer cells. |
